CYP2E1

calbc-group:ANAT, calbc-group:CHEM, calbc-group:CONC, calbc-group:GENE, calbc-group:LIVB, calbc-group:PHEN, calbc-group:PHYS, calbc-group:PROC

MSH: An ethanol-inducible cytochrome P450 enzyme that metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Substrates include alcohol; NITROSAMINES; BENZENE; URETHANE; and other low molecular weight compounds. CYP2E1 has been used as an enzyme marker in the study of alcohol abuse.,NCI: Cytochrome P450 2E1 (493 aa, ~57 kDa) is encoded by the human CYP2E1 gene. This protein plays a role in the both the metabolism of drugs, ethanol and other xenobiotics and the oxidative activation of nitrosamines.

umls-concept:C0815015

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