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skos:definition |
MSH: An enzyme that is active in the first step of choline phosphoglyceride (lecithin) biosynthesis by catalyzing the phosphorylation of choline to phosphorylcholine in the presence of ATP. Ethanolamine and its methyl and ethyl derivatives can also act as acceptors. EC 2.7.1.32.,NCI: Choline Kinase, encoded by the human CHK gene, produces phosphocholine from choline. The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. Choline kinase is the initial enzyme in the sequence and may play a regulatory role. Choline kinase also catalyzes the phosphorylation of ethanolamine. (From LocusLink and NCI)
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