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skos:definition |
MSH: A surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.,NCI: An ester of paraaminobenzoic acid, lacking the terminal diethylamino group of procaine, with anesthetic activity. Benzocaine binds to the sodium channel and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions. Depolarization of the neuronal membrane is inhibited, thereby blocking the initiation and conduction of nerve impulses.
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