Allopurinol

Source:http://linkedlifedata.com/resource/umls/id/C0002144

MSH: A XANTHINE OXIDASE inhibitor that decreases URIC ACID production. It also acts as an antimetabolite on some simpler organisms.,CSP: drug used to treat gout and other conditions in which there is an excessive buildup of uric acid.,NCI: A drug that lowers high levels of uric acid (a byproduct of metabolism) in the blood caused by some cancer treatments.,CHV: a kind of gout treatment drug,PDQ: A structural isomer of hypoxanthine. Allopurinol inhibits xanthine oxidase, an enzyme that converts oxypurines to uric acid. By blocking the production of uric acid, this agent decreases serum and urine concentrations of uric acid, thereby providing protection against uric acid-mediated end organ damage in conditions associated with excessive production of uric acid, i.e. the massive cell lysis associated with the treatment of some malignancies. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=38452&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=38452&idt

Download in:

View as