Source:http://linkedlifedata.com/resource/umls/id/C0001206
AIR: WHAT: Acromegaly: Hypersecretion of growth hormone from a pituitary tumor resulting in insidious increase in the skeleton, soft tissues and organs. WHY: Acromegaly can result in an arthropathy with initial cartilage hypertrophy resulting in widening of the cartilage space on radiographs. The cartilage then undergoes premature osteoarthritis change with productive bony change characterized by broad distal tufts in the phalanges.,MSH: A condition caused by prolonged exposure to excessive HUMAN GROWTH HORMONE in adults. It is characterized by bony enlargement of the FACE; lower jaw (PROGNATHISM); hands; FEET; HEAD; and THORAX. The most common etiology is a GROWTH HORMONE-SECRETING PITUITARY ADENOMA. (From Joynt, Clinical Neurology, 1992, Ch36, pp79-80),CSP: disorder caused by excessive secretion of somatotropin, characterized by bony enlargement of face, hands, feet, head and thorax.,NCI: A syndrome characterized by enlargement of the hands, feet, ears, nose, lips, and tongue, skin thickening and swelling o