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NCI: A genetically engineered antibody consisting of both the variable heavy chain (VH) and the light chain (VL) of an immunoglobulin. These entities are joined together by a flexible peptide linker.,MSH: A form of antibodies consisting only of the variable regions of the heavy and light chains (FV FRAGMENTS), connected by a small linker peptide. They are less immunogenic than complete immunoglobulin and thus have potential therapeutic use.
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