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PDQ: A tumor-associated melanocytic differentiation antigen. Vaccination with MART-1 antigen may stimulate a host cytotoxic T-cell response against tumor cells expressing the melanocytic differentiation antigen, resulting in tumor cell lysis. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43061&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43061&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C28724" NCI Thesaurus),NCI: Melanoma antigen recognized by T-cells 1 (118 aa, ~13 kDa) is encoded by the human MLANA gene. This protein may play a role in melanin production.,MSH: A melanosome-specific protein that plays a role in the expression, stability, trafficking, and processing of GP100 MELANOMA ANTIGEN, which is critical to the formation of Stage II MELANOSOMES. The protein is used as an antigen marker for MELANOMA cells.,NCI: A protein found on
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