Insulin Signaling Pathway

Source:http://linkedlifedata.com/resource/umls/id/C1512804

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NCI: The appropriate signaling through the insulin pathway is critical for the regulation of glucose levels and the avoidance of diabetes. Insulin forms a complex with the insulin receptor (IR) and b chains to form the active signaling complex. Through recruitment of adaptor molecules and the activation of RAS, the activated IR can cause transcriptional activation.
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