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| skos:definition |
NCI: Hypermethylation appears to be a controlled, epigenetic, heritable, and aberrant DNA methylation reaction on gene promoter regions and CpG islands associated with loss of (e.g., tumor-suppressor) gene function in diverse cellular pathways through transcriptional silencing by the formation of transcriptionally repressive chromatin.
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| skos:inScheme | |
| skos-xl:prefLabel |