Linked Life Data

DICER1

Source:http://linkedlifedata.com/resource/umls/id/C1309483

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NCI: Endoribonuclease Dicer, encoded by the human DICER1 gene, possesses an RNA helicase motif, containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. It is required by the RNA interference in cleaving double-stranded RNA as well as small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. The 21 to 23 bp double-stranded RNAs (siRNAs) generated target the selective destruction of homologous RNAs. (From OMIM, Swiss-Port, and NCI)
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