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skos:definition |
PDQ: A novel palladium-substituted bacteriochlorophyll derivative and photosensitizer with potential antitumor activity. Upon administration, inactive palladium-bacteriophephorbide is activated locally when the tumor bed is exposed to photoirradiation; the activated form induces local cytotoxic processes, resulting in local tissue damage, disruption of tumor vasculature, and tumor hypoxia and necrosis. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=483132&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=483132&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C61321" NCI Thesaurus),NCI: A novel palladium-substituted bacteriochlorophyll derivative and photosensitizer with potential antitumor activity. Upon administration, inactive palladium-bacteriopheophorbide is activated locally when the tumor bed is exposed to photoirradiation; the activated f
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umls:relation |
http://linkedlifedata.com/resource/umls/relation/R60455459,
http://linkedlifedata.com/resource/umls/relation/R60453277,
http://linkedlifedata.com/resource/umls/relation/R69721309,
http://linkedlifedata.com/resource/umls/relation/R69790726,
http://linkedlifedata.com/resource/umls/relation/R69810878,
http://linkedlifedata.com/resource/umls/relation/R32168263,
http://linkedlifedata.com/resource/umls/relation/R44810126,
http://linkedlifedata.com/resource/umls/relation/R128630604
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