avasimibe

Source:http://linkedlifedata.com/resource/umls/id/C0965226

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Predicate	Object
rdf:type	umls-semnetwork:T109, umls-semnetwork:T121, skos:Concept
calbc:hasCorrelation	calbc-group:CHEM, calbc-group:CONC
skos:definition	NCI: An orally bioavailable inhibitor of acyl-Coenzyme A:cholesterol acyltransferase (ACAT) that prevents cholesterol deposition in the arterial wall. Research was discontinued due to difficulties in assaying the effects of avasimibe on preventing plaque formation and due to its ability to increase the activity of Cytochrome P450 3A4, thus increasing the removal of other drugs from the body.
skos:inScheme	lld:umls
skos:broader	umls-concept:C0000979
skos:narrower	umls-concept:C0533127
skos-xl:prefLabel	umls-label:A7164726
skos-xl:altLabel	umls-label:A16756838, umls-label:A16761365, umls-label:A7164769
umls:relation	http://linkedlifedata.com/resource/umls/relation/R109627159, http://linkedlifedata.com/resource/umls/relation/R109643097, http://linkedlifedata.com/resource/umls/relation/R33849471, http://linkedlifedata.com/resource/umls/relation/R128615819, http://linkedlifedata.com/resource/umls/relation/R128615820