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skos:definition |
MSH: Cellular proteins and protein complexes that transport amino acids across biological membranes.,NCI: Amino Acid Transporter proteins carry organic compounds containing an amino (-NH2) and a carboxyl (-COOH) group through solubility barriers, such as aqueous body fluids, lipid membranes or across epithelial layers. After binding substrate, transmembrane transporters often undergo an energy-dependent conformational change that moves the substrate across the membrane with (symport) or against (antiport) concentration gradients.
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