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skos:definition |
NCI: A commercial combination preparation, by Purdue, containing a standardized senna concentrate and docusate sodium with laxative and stool softening activity. Senna concentrate consists of the anthraquinone glycosides sennosides extracted from senna leaves. Sennosides act on and irritate the lining of the intestine wall, thereby causing increased intestinal muscle contractions leading to vigorous bowel movement and relief of constipation. Docusate sodium, an anionic surfactant, softens the stool for smoother and easier evacuation.
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