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skos:definition |
MSH: Inbred strains of animals that are genetically identical except at a single locus, or a few specified loci, so that their known genetic differences are expressed in the same genetic background. A congenic strain is produced by outbreeding a strain and then eliminating the background by many generations of backcrosses while maintaining the desired genetic differences by selection of progeny. (Dorland, 28th ed)
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