skos:definition |
GO: Thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone; usually approximately 0.1 um wide, 5-10 um long, can be up to 50 um long in axon growth cones; contains a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward. [GOC:mah, ISBN:0815316194],NCI: A slender projection of the plasma membrane at the leading edge of migrating cells. This protrusion contains bundles of long, crosslinked actin filaments.
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