Linked Life Data

TMSB15

Source:http://linkedlifedata.com/resource/umls/id/C0532005

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NCI: Thymosin Beta-15 (Thymosin-Beta Family) may be an actin-binding protein and positive cell motility factor that opposes the activity of motility suppressor KAI1. Involved in metastasis and prostate cancer, TMSB15 may be a new target for therapy. (from OMIM and NCI),NCI: Thymosin beta-15, a member of the thymosin-beta family, is an actin-binding protein that enhances cell motility. It is expressed in advanced prostate cancer, but not in the normal prostate or in benign prostatic hyperplasia, suggesting its potential as a marker for prostate carcinoma progression. Thymosin-beta-15 levels correlate with the Gleason tumor grade. Thymosin-beta-15 and the motility suppressor KAI1 may provide alternate pathway targets for cancer therapy. (from OMIM 601587 and NCI)
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