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skos:definition |
NCI: A recombinant form of endogenous human growth hormone (GH), a polypeptide produced by the anterior lobe of the human pituitary gland. GH exhibits growth-promoting effects and metabolic effects on carbohydrate, fat, protein and bone metabolism. GH stimulates protein synthesis and the uptake of amino acids into cells, and induces lipolysis in adipose tissues. The secretion of GH increases with sexual maturation and then declines steadily.,MSH: Growth hormone (somatotropin) can be synthesized with methods of recombinant DNA technology. Since action of GH is highly species-specific, recombinant growth hormones of several species (including humans, cows, and pigs) have been developed. They have been used to stimulate growth.
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