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skos:definition |
NCI: Nuclear factor erythroid 2-related factor 2 protein (605 aa, ~68 kDa) is encoded by the human NFE2L2 gene. This transcription factor is involved in cellular antioxidant defense and beta-globin activity modulation.,MSH: A basic-leucine zipper transcription factor that was originally described as a transcriptional regulator controlling expression of the BETA-GLOBIN gene. It may regulate the expression of a wide variety of genes that play a role in protecting cells from oxidative damage.
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