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skos:definition |
MSH: Acidic sulfated integral membrane glycoproteins expressed in several alternatively spliced and variable glycosylated forms on a wide variety of cell types including mature T-cells, B-cells, medullary thymocytes, granulocytes, macrophages, erythrocytes, and fibroblasts. CD44 antigens are the principle cell surface receptors for hyaluronate and this interaction mediates binding of lymphocytes to high endothelial venules. (From Abbas et al., Cellular and Molecular Immunology, 2d ed, p156),CSP: transmembrane hyaluronate receptor family of molecules; mediates immune cell adhesion, motility, and immune cell cytokine release.,NCI: CD44 antigen (742 aa, 82 kD) is a cell adhesion process protein that is encoded by the human CD44 gene and may have roles in cell-cell adhesion and cell-matrix adhesion.
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