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skos:definition |
NCI: Expressed in T-cells and natural killer cells by interleukin-2-induced ITK Gene (TEC Tyr Kinase Family), 620-aa 72-kDa intracellular IL2-Inducible T-Cell (tyrosine) Kinase contains an SH2, SH3, and PH domain, appears to localize to cell surface receptors (TCR,CD28, CD2) after stimulation, and plays a role in T-cell proliferation and differentiation. (NCI)
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