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rdf:type |
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calbc:hasCorrelation |
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skos:exactMatch |
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skos:definition |
MSH: A family of transcription factors characterized by the presence of highly conserved calcineurin- and DNA-binding domains. NFAT proteins are activated in the CYTOPLASM by the calcium-dependent phosphatase CALCINEURIN. They transduce calcium signals to the nucleus where they can interact with TRANSCRIPTION FACTOR AP-1 or NF-KAPPA B and initiate GENETIC TRANSCRIPTION of GENES involved in CELL DIFFERENTIATION and development. NFAT proteins stimulate T-CELL activation through the induction of IMMEDIATE-EARLY GENES such as INTERLEUKIN-2.
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skos:inScheme |
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skos:narrower |
umls-concept:C0213009,
umls-concept:C0379844,
umls-concept:C0905644,
umls-concept:C1101121,
umls-concept:C1172116,
umls-concept:C1311857,
umls-concept:C1452220,
umls-concept:C1527443,
umls-concept:C1530005,
umls-concept:C1530015,
umls-concept:C1530016,
umls-concept:C1530017,
umls-concept:C1530018,
umls-concept:C1530023,
umls-concept:C1530025
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skos-xl:prefLabel |
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skos-xl:altLabel |
umls-label:A17930992,
umls-label:A17954767,
umls-label:A17979061,
umls-label:A17979062,
umls-label:A18002707,
umls-label:A18026455,
umls-label:A18026456,
umls-label:A18050727,
umls-label:A8417054,
umls-label:A8417055,
umls-label:A8417081,
umls-label:A8417093,
umls-label:A8417923,
umls-label:A8417929,
umls-label:A8417936,
umls-label:A8417937,
umls-label:A8424050,
umls-label:A8424051,
umls-label:A8424230,
umls-label:A8435145
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umls:relation |
http://linkedlifedata.com/resource/umls/relation/R119414718,
http://linkedlifedata.com/resource/umls/relation/R44821863,
http://linkedlifedata.com/resource/umls/relation/R44815026,
http://linkedlifedata.com/resource/umls/relation/R44821883,
http://linkedlifedata.com/resource/umls/relation/R32152034,
http://linkedlifedata.com/resource/umls/relation/R32152035,
http://linkedlifedata.com/resource/umls/relation/R32152046,
http://linkedlifedata.com/resource/umls/relation/R32152039,
http://linkedlifedata.com/resource/umls/relation/R44811273,
http://linkedlifedata.com/resource/umls/relation/R120689805,
http://linkedlifedata.com/resource/umls/relation/R120689806,
http://linkedlifedata.com/resource/umls/relation/R120689808,
http://linkedlifedata.com/resource/umls/relation/R120689809,
http://linkedlifedata.com/resource/umls/relation/R120689810,
http://linkedlifedata.com/resource/umls/relation/R120689811,
http://linkedlifedata.com/resource/umls/relation/R120689812,
http://linkedlifedata.com/resource/umls/relation/R120689813,
http://linkedlifedata.com/resource/umls/relation/R120689815,
http://linkedlifedata.com/resource/umls/relation/R120689817,
http://linkedlifedata.com/resource/umls/relation/R120689818,
http://linkedlifedata.com/resource/umls/relation/R120689819,
http://linkedlifedata.com/resource/umls/relation/R120689821,
http://linkedlifedata.com/resource/umls/relation/R120689822,
http://linkedlifedata.com/resource/umls/relation/R120689823,
http://linkedlifedata.com/resource/umls/relation/R120689825,
http://linkedlifedata.com/resource/umls/relation/R120689826,
http://linkedlifedata.com/resource/umls/relation/R120689827,
http://linkedlifedata.com/resource/umls/relation/R120689828,
http://linkedlifedata.com/resource/umls/relation/R120689829,
http://linkedlifedata.com/resource/umls/relation/R120689830,
http://linkedlifedata.com/resource/umls/relation/R120689831,
http://linkedlifedata.com/resource/umls/relation/R120689832,
http://linkedlifedata.com/resource/umls/relation/R120689833,
http://linkedlifedata.com/resource/umls/relation/R120689834,
http://linkedlifedata.com/resource/umls/relation/R120689835,
http://linkedlifedata.com/resource/umls/relation/R120689836,
http://linkedlifedata.com/resource/umls/relation/R120689837,
http://linkedlifedata.com/resource/umls/relation/R120689816,
http://linkedlifedata.com/resource/umls/relation/R120689820,
http://linkedlifedata.com/resource/umls/relation/R120689807,
http://linkedlifedata.com/resource/umls/relation/R120689824,
http://linkedlifedata.com/resource/umls/relation/R120689814,
http://linkedlifedata.com/resource/umls/relation/R71218347,
http://linkedlifedata.com/resource/umls/relation/R129024463,
http://linkedlifedata.com/resource/umls/relation/R129024464,
http://linkedlifedata.com/resource/umls/relation/R129024465,
http://linkedlifedata.com/resource/umls/relation/R129024473,
http://linkedlifedata.com/resource/umls/relation/R129024472,
http://linkedlifedata.com/resource/umls/relation/R129024471,
http://linkedlifedata.com/resource/umls/relation/R129024466,
http://linkedlifedata.com/resource/umls/relation/R129024468,
http://linkedlifedata.com/resource/umls/relation/R129024470
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