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skos:definition |
MSH: Molecules or ions formed by the incomplete one-electron reduction of oxygen. These reactive oxygen intermediates include SINGLET OXYGEN; SUPEROXIDES; PEROXIDES; HYDROXYL RADICAL; and HYPOCHLOROUS ACID. They contribute to the microbicidal activity of PHAGOCYTES, regulation of signal transduction and gene expression, and the oxidative damage to NUCLEIC ACIDS; PROTEINS; and LIPIDS.,NCI: A substance that can produce oxygen byproducts of metabolism that can cause damage to cells.,NCI: Organic or inorganic chemicals that contain an oxygen atom with an unpaired electron. This unstable electron configuration causes these chemicals to be highly reactive with other molecules.
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