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MSH: A cyclodecane isolated from the bark of the Pacific yew tree, TAXUS BREVIFOLIA. It stabilizes MICROTUBULES in their polymerized form leading to cell death.,CSP: extract from the Pacific yew tree Taxus brevifolia which stabilizes microtubles and is therefore used as a cytologic probe for microtubule function, and clinically as an antineoplastic; do not confuse with a bile salt laxative with the trade name Taxol.,NCI: A drug used to treat breast cancer, ovarian cancer, and AIDS-related Kaposi sarcoma. It is also used together with another drug to treat non-small cell lung cancer. Paclitaxel is also being studied in the treatment of other types of cancer. It blocks cell growth by stopping cell division and may kill cancer cells. It is a type of antimitotic agent.,NCI: Any formulation containing paclitaxel, an antimitotic taxane.,PDQ: A compound extracted from the Pacific yew tree Taxus brevifolia with antineoplastic activity. Paclitaxel binds to tubulin and inhibits the disassembly of microtubules, thereby
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