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skos:definition |
MSH: A condition characterized by persistent spasms (SPASM) involving multiple muscles, primarily in the lower limbs and trunk. The illness tends to occur in the fourth to sixth decade of life, presenting with intermittent spasms that become continuous. Minor sensory stimuli, such as noise and light touch, precipitate severe spasms. Spasms do not occur during sleep and only rarely involve cranial muscles. Respiration may become impaired in advanced cases. (Adams et al., Principles of Neurology, 6th ed, p1492; Neurology 1998 Jul;51(1):85-93),NCI: A rare neurologic disorder characterized by muscle rigidity. It usually affects the axial muscles and eventually extends to the proximal limb muscles. It is associated with muscle spasms which may lead to muscle damage and fractures.
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