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skos:definition |
MSH: A lymphohematopoietic cytokine that plays a role in regulating the proliferation of ERYTHROID PRECURSOR CELLS. It induces maturation of MEGAKARYOCYTES which results in increased production of BLOOD PLATELETS. Interleukin-11 was also initially described as an inhibitor of ADIPOGENESIS of cultured preadipocytes.,CSP: cloned from a primate stromal cell line; plays a role in megakaryocyte proliferation and B cell differentiation.,NCI: One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-11 is made by support cells in the bone marrow. It causes the growth of several types of blood cells. Oprelvekin (interleukin-11 made in the laboratory) is used as a biological response modifier to increase the number of platelets, especially in patients receiving chemotherapy for cancer. Interleukin-11 is a type of cytokine.,PDQ: A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine interleukin 11 (IL-11). Secreted
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skos:inScheme |
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skos:broader |
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skos-xl:prefLabel |
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umls:relation |
http://linkedlifedata.com/resource/umls/relation/R28523298,
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http://linkedlifedata.com/resource/umls/relation/R64592994,
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http://linkedlifedata.com/resource/umls/relation/R28446170,
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http://linkedlifedata.com/resource/umls/relation/R120542073,
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http://linkedlifedata.com/resource/umls/relation/R120542096,
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http://linkedlifedata.com/resource/umls/relation/R120542084,
http://linkedlifedata.com/resource/umls/relation/R120542075,
http://linkedlifedata.com/resource/umls/relation/R71359813,
http://linkedlifedata.com/resource/umls/relation/R128979521,
http://linkedlifedata.com/resource/umls/relation/R128979522,
http://linkedlifedata.com/resource/umls/relation/R71223959,
http://linkedlifedata.com/resource/umls/relation/R71168782,
http://linkedlifedata.com/resource/umls/relation/R71224060,
http://linkedlifedata.com/resource/umls/relation/R71168896,
http://linkedlifedata.com/resource/umls/relation/R71114258,
http://linkedlifedata.com/resource/umls/relation/R71279586,
http://linkedlifedata.com/resource/umls/relation/R71338585,
http://linkedlifedata.com/resource/umls/relation/R71035032,
http://linkedlifedata.com/resource/umls/relation/R71118180,
http://linkedlifedata.com/resource/umls/relation/R71173027
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