|
skos:definition |
MSH: Glycoproteins expressed on all mature T-cells, thymocytes, and a subset of mature B-cells. Antibodies specific for CD5 can enhance T-cell receptor-mediated T-cell activation. The B-cell-specific molecule CD72 is a natural ligand for CD5. (From Abbas et al., Cellular and Molecular Immunology, 2d ed, p156),CSP: lymphocyte marker expressed on T and the Ly-1 subset of B cells; sends accessory signals necessary for CD3-mediated T cell activation, possibly via phosphorylation of inositol phosphate; Ly-1 B cells have a propensity for autoantibody production.,NCI: T-cell surface glycoprotein CD5 (495 aa, ~54 kDa) is encoded by the human CD5 gene. This protein may be involved in regulating the proliferation of T-cells.
|
