|
skos:definition |
NCI: A protein that is made by many different types of cells and is involved in processes that take place both inside and outside of the cell. It is made in larger amounts in inflammatory diseases such as rheumatoid arthritis, and in some types of cancer. It is being studied as a biomarker for breast cancer.,MSH: A 13.2-kDa member of the S-100 family of calcium-binding proteins that can form homo- or heterocomplexes with CALGRANULIN A and a variety of other proteins. The calgranulin A/B heterodimer is known as LEUKOCYTE L1 ANTIGEN COMPLEX. Calgranulin B is expressed at high concentrations in GRANULOCYTES during early monocyte differentiation, and serum calgranulin B levels are elevated in many inflammatory disorders such as CYSTIC FIBROSIS.,NCI: Constitutively expressed in epithelial cells and in macrophages within inflamed tissues by human S100A9 Gene (S100 Family), 114-aa 13-kDa S100 Calcium Binding Protein A9, containing 2 EF-hand calcium-binding motifs, may inhibit protein kinases and interact with interm
|
