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skos:definition |
MSH: Membrane-bound compartments which contain transmitter molecules. Synaptic vesicles are concentrated at presynaptic terminals. They actively sequester transmitter molecules from the cytoplasm. In at least some synapses, transmitter release occurs by fusion of these vesicles with the presynaptic membrane, followed by exocytosis of their contents.,CSP: small membrane-bound structures behind a presynaptic membrane, containing neurotransmitters; when depolarization occurs they fuse with the presynaptic membrane and release the neurotransmitter into the synaptic cleft.,GO: A secretory organelle, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and is secreted these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane. [PMID:10099709]
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