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skos:definition |
MSH: A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7),CSP: spastic weakness of the muscles innervated by the cranial nerves, i.e., the muscle of the face, pharynx, and tongue, due to bilateral lesions of the corticospinal tract.,MEDLINEPLUS: <p>Progressive supranuclear palsy (PSP) is a rare <a href='http://www.nlm.nih.gov/medlineplus/braindiseases.html'>brain disease</a>. It affects brain cells that control the movement of your eyes. This leads to serious and permanent problems with balance and the way you walk. It usuall
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