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skos:definition |
MSH: A 14-amino acid peptide named for its ability to inhibit pituitary GROWTH HORMONE release, also called somatotropin release-inhibiting factor. It is expressed in the central and peripheral nervous systems, the gut, and other organs. SRIF can also inhibit the release of THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; and GLUCAGON besides acting as a neurotransmitter and neuromodulator. In a number of species including humans, there is an additional form of somatostatin, SRIF-28 with a 14-amino acid extension at the N-terminal.,CSP: any of several cyclic tetradecapeptides elaborated primarily by the median eminence of the hypothalamus and by the delta cells of the pancreatic islets; they inhibit release of a variety of hormones, including growth hormone, thyrotropin, corticotropin, insulin, glucagon, gastrin, secretin and renin.,NCI: Expressed primarily by human SST Gene (Somatostatin Family) in the hypothalamic median eminence and in pancreatic delta cells, secreted 116-aa 13-kDa (precursor) Somatostatin
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