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skos:definition |
MSH: Cell surface proteins that bind cyclic AMP with high affinity and trigger intracellular changes which influence the behavior of cells. The best characterized cyclic AMP receptors are those of the slime mold Dictyostelium discoideum. The transcription regulator CYCLIC AMP RECEPTOR PROTEIN of prokaryotes is not included nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins which are the regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASES.,CSP: cell surface receptor found in slime mold Dictyostelium discoideum, where cyclic AMP functions both intra- and extra-cellularly; or, the CRP of E. coli and other systems, a cystolic, DNA-binding protein of the steroid receptor type.
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