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skos:definition |
CSP: since the 2 subtypes are distinctly different receptors, use MUSCARINIC or NICOTINIC whenever possible; use this general term only for unspecified binding of acetylcholine and related ligands.,MSH: Cell surface proteins that bind acetylcholine with high affinity and trigger intracellular changes influencing the behavior of cells. Cholinergic receptors are divided into two major classes, muscarinic and nicotinic, based originally on their affinity for nicotine and muscarine. Each group is further subdivided based on pharmacology, location, mode of action, and/or molecular biology.
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