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rdf:type |
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calbc:hasCorrelation |
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skos:exactMatch |
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skos:definition |
MSH: An serine-threonine protein kinase that requires the presence of physiological concentrations of CALCIUM and membrane PHOSPHOLIPIDS. The additional presence of DIACYLGLYCEROLS markedly increases its sensitivity to both calcium and phospholipids. The sensitivity of the enzyme can also be increased by PHORBOL ESTERS and it is believed that protein kinase C is the receptor protein of tumor-promoting phorbol esters.,CSP: nonEC.,NCI: An enzyme found throughout the body's tissues and organs. Several forms of PKC are involved in many cellular functions. PKC is being studied in the treatment of cancer.,NCI: A family of serine/threonine protein kinases that have a structurally conserved catalytic subunit and a regulatory subunit that are connected by a hinge domain.
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skos:inScheme |
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skos:broader |
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skos:narrower |
umls-concept:C0033638,
umls-concept:C0070753,
umls-concept:C0072371,
umls-concept:C0138861,
umls-concept:C0171420,
umls-concept:C0217770,
umls-concept:C0254445,
umls-concept:C0256015,
umls-concept:C0256813,
umls-concept:C0257291,
umls-concept:C0258823,
umls-concept:C0379298,
umls-concept:C0386511,
umls-concept:C0386513,
umls-concept:C0536985,
umls-concept:C0758622,
umls-concept:C0759025,
umls-concept:C0767520,
umls-concept:C0908507,
umls-concept:C1120672,
umls-concept:C1307932,
umls-concept:C1447170,
umls-concept:C1451038,
umls-concept:C1455307,
umls-concept:C1506190,
umls-concept:C1506742,
umls-concept:C1613877,
umls-concept:C1722757,
umls-concept:C2001673,
umls-concept:C2603556,
umls-concept:C2713433
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skos-xl:prefLabel |
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skos-xl:altLabel |
umls-label:A0033976,
umls-label:A0034069,
umls-label:A0100988,
umls-label:A0100989,
umls-label:A0106403,
umls-label:A0360541,
umls-label:A0487514,
umls-label:A0487515,
umls-label:A1038629,
umls-label:A16765103,
umls-label:A17879611,
umls-label:A17903714,
umls-label:A17903715,
umls-label:A17976089,
umls-label:A18023501,
umls-label:A18023504,
umls-label:A18649379,
umls-label:A18686353,
umls-label:A18686354,
umls-label:A19033786,
umls-label:A19042466,
umls-label:A1916794,
umls-label:A1929927,
umls-label:A7573232,
umls-label:A7583035,
umls-label:A8418742,
umls-label:A8418743,
umls-label:A8422344
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umls:relation |
http://linkedlifedata.com/resource/umls/relation/R28414899,
http://linkedlifedata.com/resource/umls/relation/R28488532,
http://linkedlifedata.com/resource/umls/relation/R28488534,
http://linkedlifedata.com/resource/umls/relation/R28434826,
http://linkedlifedata.com/resource/umls/relation/R28511804,
http://linkedlifedata.com/resource/umls/relation/R32106212,
http://linkedlifedata.com/resource/umls/relation/R120425822,
http://linkedlifedata.com/resource/umls/relation/R120425823,
http://linkedlifedata.com/resource/umls/relation/R120425825,
http://linkedlifedata.com/resource/umls/relation/R120425826,
http://linkedlifedata.com/resource/umls/relation/R120425827,
http://linkedlifedata.com/resource/umls/relation/R120425828,
http://linkedlifedata.com/resource/umls/relation/R120425829,
http://linkedlifedata.com/resource/umls/relation/R120425830,
http://linkedlifedata.com/resource/umls/relation/R120425832,
http://linkedlifedata.com/resource/umls/relation/R120425834,
http://linkedlifedata.com/resource/umls/relation/R120425835,
http://linkedlifedata.com/resource/umls/relation/R120425836,
http://linkedlifedata.com/resource/umls/relation/R120425838,
http://linkedlifedata.com/resource/umls/relation/R120425839,
http://linkedlifedata.com/resource/umls/relation/R120425840,
http://linkedlifedata.com/resource/umls/relation/R120425842,
http://linkedlifedata.com/resource/umls/relation/R120425843,
http://linkedlifedata.com/resource/umls/relation/R120425844,
http://linkedlifedata.com/resource/umls/relation/R120425845
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