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MSH: A soluble substance elaborated by antigen- or mitogen-stimulated T-LYMPHOCYTES which induces DNA synthesis in naive lymphocytes.,CSP: interleukin 2 is produced by T cells in response to antigenic or mitogenic stimulation and the signal carried by interleukin 1; it stimulates the proliferation of T cells bearing specific receptors for interleukin 2, expressed by antigenically stimulated T cells; it also seems to induce production of interferon gamma, and is used as an anticancer agent in a wide variety of solid malignant tumors.,NCI: Encoded by human IL2 Gene, Interleukin-2 is a secreted cytokine important for proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). IL2 expression in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling expression of a single gene. Targeted disruption of a similar gene in mice leads to ulcerative colitis-li
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