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skos:definition |
MSH: Small chromosomal proteins (approx 12-20 kD) possessing an open, unfolded structure and attached to the DNA in cell nuclei by ionic linkages. Classification into the various types (designated histone I, histone II, etc.) is based on the relative amounts of arginine and lysine in each.,CSP: small chromosomal proteins (approx 12-20 kD) possessing an open, unfolded structure and attached to the DNA in cell nuclei by ionic linkages; classification into the various types (designated histone I, histone II, etc) is based on the relative amounts of arginine and lysine in each.,NCI: A type of protein found in chromosomes. Histones bind to DNA, help give chromosomes their shape, and help control the activity of genes.,NCI: Major protein component of chromatin. Highly conserved basic proteins, originally classified into classes based on the relative amounts of arginine and lysine in each protein. The various classes are now termed H1, H2A, H2B, H3, and H4. In chromatin, they are found in an octamer, containing two
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