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skos:definition |
MSH: The isotopic compound of hydrogen of mass 2 (deuterium) with oxygen. (From Grant & Hackh's Chemical Dictionary, 5th ed) It is used to study mechanisms and rates of chemical or nuclear reactions, as well as biological processes.,CSP: isotopic compound of hydrogen of mass 2 (deuterium) with oxygen; used to study mechanisms and rates of chemical or nuclear reactions, as well as biological processes.,NCI: A stable, non-radioactive isotopic form of water, containing 2 atoms of deuterium (D) and one atom of oxygen (2D2O), with DNA-labeling activity. Upon ingestion of deuterium oxide, 2H is incorporated into the deoxyribose moiety of DNA of newly divided cells. Rapidly dividing cells, as in the case of B-cell chronic lymphocytic leukemia (B-CLL), can be labeled with deuterium oxide and measured using gas chromatography and/or mass spectrometry.
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