Source:http://linkedlifedata.com/resource/umls/id/C0011259
MSH: An alkaloid isolated from Colchicum autumnale L. and used as an antineoplastic.,NCI: A colchicine analog with potential antimitotic and antineoplastic activities. Demecolcine acid binds to the colchicine-binding site of tubulin, inhibiting its polymerization into microtubules, causing cell cycle arrest at metaphase and preventing cell division.