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rdf:type |
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calbc:hasCorrelation |
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skos:exactMatch |
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skos:definition |
MSH: Members of the class of neutral glycosphingolipids. They are the basic units of SPHINGOLIPIDS. They are sphingoids attached via their amino groups to a long chain fatty acyl group. They abnormally accumulate in FABRY DISEASE.,CSP: N-acyl sphingosine, a neutral lipid with 2 long aliphatic tails, the parent compound of sphingolipids.,NCI: A type of lipid (fat) found in the membranes of cells and the covers of nerves. Some ceramides are important in signal transduction (the process by which a cell responds to substances in its environment) and may cause some types of cells to die. Ceramides are being studied in the treatment of cancer.,PDQ: One of a number of a class of sphingolipids, N-acyl derivatives with long chains. Ceramide is the core molecule for the synthesis of sphingomyelin, an essential lipid for myelination and neurotransmission; it may function as a second messenger to stimulate differentiation, inhibit proliferation, and induce apoptosis. Check for "http://www.cancer.gov/Search/ClinicalTrials
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skos:inScheme |
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skos:broader |
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skos:narrower |
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skos-xl:prefLabel |
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skos-xl:altLabel |
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umls:relation |
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