Linked Life Data

999140

Source:http://linkedlifedata.com/resource/pubmed/id/999140

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6 PT. 1
pubmed:dateCreated
1977-1-29
pubmed:abstractText
The response characteristics of auditory-nerve fibers in normal cats are compared with those in cats exposed to kanamycin and high-intensity sounds. The pathophysiology is characterized by an elevation of the tuning-curve "tips," which is sometimes associated with hypersensitivity of the "tails". Plots of unit thresholds are correlated with patterns of sensory-cell losses in the cochlea. There can be significant shifts in unit threshold without significant loss of hair cells; however, significant hair cell loss is always accompanied by highly abnormal unit thresholds. The presence of inner hair cells seems to be essential for the long-term survival of spiral ganglion cells. An incidental observation is that in the "normal" animal there is almost always a prominent "notch" at 3-4 kHz in the plots of threshold at characteristic frequency, which may have been produced by environmental noise.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0003-4894
pubmed:author
pubmed:issnType
Print
pubmed:volume
85
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
752-68
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:articleTitle
Auditory-nerve activity in cats exposed to ototoxic drugs and high-intensity sounds.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.