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9990465
Source:
http://linkedlifedata.com/resource/pubmed/id/9990465
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54
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Statements in which the resource exists as a subject.
Predicate
Object
rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0016829
,
umls-concept:C0220781
,
umls-concept:C0243072
,
umls-concept:C0243077
,
umls-concept:C0597295
,
umls-concept:C0762202
,
umls-concept:C1707689
,
umls-concept:C1883254
pubmed:issue
1
pubmed:dateCreated
1999-4-13
pubmed:abstractText
A reduction of the tetracyclic skeleton of sordarins and sordaricins to a cyclopentane ring bearing the pharmacophore functional groups led to new derivatives retaining part of their in vitro and whole-cell activity.
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Antifungal Agents
,
http://linkedlifedata.com/resource/pubmed/chemical/Diterpenes
,
http://linkedlifedata.com/resource/pubmed/chemical/Fungal Proteins
,
http://linkedlifedata.com/resource/pubmed/chemical/Protein Synthesis Inhibitors
,
http://linkedlifedata.com/resource/pubmed/chemical/sordaricin
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0960-894X
pubmed:author
pubmed-author:CuevasJ CJC
,
pubmed-author:LavanderaJ LJL
,
pubmed-author:MartosJ LJL
pubmed:issnType
Print
pubmed:day
4
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
103-8
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed-meshheading:9990465-Animals
,
pubmed-meshheading:9990465-Antifungal Agents
,
pubmed-meshheading:9990465-Biological Availability
,
pubmed-meshheading:9990465-Candida albicans
,
pubmed-meshheading:9990465-Cell-Free System
,
pubmed-meshheading:9990465-Diterpenes
,
pubmed-meshheading:9990465-Dose-Response Relationship, Drug
,
pubmed-meshheading:9990465-Drug Design
,
pubmed-meshheading:9990465-Drug Evaluation, Preclinical
,
pubmed-meshheading:9990465-Fungal Proteins
,
pubmed-meshheading:9990465-Mice
,
pubmed-meshheading:9990465-Microbial Sensitivity Tests
,
pubmed-meshheading:9990465-Models, Molecular
,
pubmed-meshheading:9990465-Protein Synthesis Inhibitors
,
pubmed-meshheading:9990465-Rats
,
pubmed-meshheading:9990465-Structure-Activity Relationship
pubmed:year
1999
pubmed:articleTitle
Design and synthesis of simplified sordaricin derivatives as inhibitors of fungal protein synthesis.
pubmed:affiliation
Glaxo Wellcome, S.A., Research Department, Parque Tecnológico de Madrid, Spain.
pubmed:publicationType
Journal Article
,
Research Support, Non-U.S. Gov't