Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1977-1-25
pubmed:abstractText
Small intestinal calcium transport adapts to dietary calcium restriction, but conservation of calcium by the ileum is incomplete. To examine the role of large intestine in calcium homeostasis, weight-matched growing rats were placed on semisynthetic diets containing 1.2 or 0.02% calcium. After 3 to 4 weeks, net calcium movements in cecum and colon (large bowel excluding cecum and distal rectum) were studied in vivo by perfusing a 0.4, 0.8, or 3.4 mM calcium solution. In animals taking 1.2% calcium, the cecum absorbed calcium actively at 0.8 mM; the colon showed net secretion except at 3.4 mM. In calcium-restricted animals, the cecum absorbed at all concentrations; the colon reduced secretion at 0.4 mM, converted to net absorption at 0.8 mM, and greatly increased net absorption at 3.4 mM. These observations suggest that the large intestine may have a role in calcium homeostasis, particularly when dietary calcium is restricted.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0016-5085
pubmed:author
pubmed:issnType
Print
pubmed:volume
71
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1039-42
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Intestinal adaptation to dietary calcium restriction: in vivo cecal and colonic calcium transport in the rat.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.