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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1976-11-21
pubmed:abstractText
The secretion of oestradiol and androstenedione was investigated in sheep by cannulating both ovarian veins in situ. The mean ovarian blood flow (ml/min +/- SE) was significantly higher on the side containing the corpus luteum (7.67 +/- 1.36) than on the contralateral side (4.93 +/- 0.85). The mean secretion (ng/min +/- SE) of oestradiol (1.09 +/- 0.36) and androstenedione (1.52 +/- 0.16) was higher on the side containing at least one large follicle (diameter greater than 4 mm) than on the contralateral side (0.19 +/- 0.05 and 0.62 +/- 0.21, respectively). The secretion of oestradiol was unchanged following enucleation of the corpus luteum but fell to very low levels (0.062 +/- 0.022 ng/min) after enucleation of follicles diameter greater than 4 mm. The secretion of androstenedione fell significantly after enucleation of both corpus luteum and largefollicles. These results suggest that during the luteal phase in the sheep oestradiol is secreted virtually exclusively by the largest non-atretic Graafian follicle. Androstenedione in contrast arises from both follicle, corpus luteum and possibly stroma.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0001-5598
pubmed:author
pubmed:issnType
Print
pubmed:volume
83
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
402-9
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
The source of ovarian oestradiol and androstenedione in the sheep during the luteal phase.
pubmed:publicationType
Journal Article