Linked Life Data

9878861

Source:http://linkedlifedata.com/resource/pubmed/id/9878861

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1999-2-1
pubmed:abstractText
We have cloned a mouse homologue of semaphorin K1 cDNA. Sequence analysis has predicted that the mouse semaphorin K1 encodes a 664 amino acid protein and contains a characteristic semaphorin domain in the N terminus followed by an immunoglobulin-like domain and a glycosylphosphatidylinositol anchoring sequence in the C terminus. In addition, this molecule has a RGD motif within the semaphorin domain. There is a high degree of amino acid identity between mouse and human semaphorin K1(89.5%). Northern blot analysis has revealed that the highest expression is detected in the nervous system and the expression level increases during neural development. Moreover, moderate expression is also detected in the immune system such as thymus and spleen. Thus, semaphorin K1 may play essential roles not only in the nervous system but also in the immune system.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0006-3002
pubmed:author
pubmed:issnType
Print
pubmed:day
22
pubmed:volume
1443
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
419-22
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Molecular cloning and expression of murine homologue of semaphorin K1 gene.
pubmed:affiliation
Mitsubishi Kasei Institute of Life Sciences, 11 Minamiooya, Machida-shi, Tokyo 194, Japan.
pubmed:publicationType
Journal Article