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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1999-3-9
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pubmed:abstractText |
Dowex-50W-H+ was used to catalyze the highly selective desialylation of polysialylated ganglio-N-tetraose series gangliosides to yield primarily GM1. High performance thin-layer chromatographic analysis of recovered lipid indicated that 60-70% of the recovered ganglioside was GM1. Identification of the major product as GM1 was confirmed by proton NMR spectra and lack of sialic acid release by Vibrio cholerae sialidase.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0022-2275
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
160-3
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9869662-Animals,
pubmed-meshheading:9869662-Anion Exchange Resins,
pubmed-meshheading:9869662-Brain Chemistry,
pubmed-meshheading:9869662-Cattle,
pubmed-meshheading:9869662-Chromatography, High Pressure Liquid,
pubmed-meshheading:9869662-G(M1) Ganglioside,
pubmed-meshheading:9869662-Gangliosides,
pubmed-meshheading:9869662-Magnetic Resonance Spectroscopy,
pubmed-meshheading:9869662-Neuraminidase,
pubmed-meshheading:9869662-Oligosaccharides,
pubmed-meshheading:9869662-Resins, Synthetic,
pubmed-meshheading:9869662-Sialic Acids,
pubmed-meshheading:9869662-Vibrio cholerae
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pubmed:year |
1999
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pubmed:articleTitle |
A simple, nonenzymatic method for desialylating polysialylated ganglio-N-tetraose series gangliosides to produce GM1.
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pubmed:affiliation |
Department of Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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