| pubmed-article:9864403 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9864403 | lifeskim:mentions | umls-concept:C0006142 | lld:lifeskim |
| pubmed-article:9864403 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:9864403 | lifeskim:mentions | umls-concept:C0021753 | lld:lifeskim |
| pubmed-article:9864403 | lifeskim:mentions | umls-concept:C0600251 | lld:lifeskim |
| pubmed-article:9864403 | lifeskim:mentions | umls-concept:C0079189 | lld:lifeskim |
| pubmed-article:9864403 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:9864403 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:9864403 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:9864403 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:9864403 | pubmed:dateCreated | 1999-3-22 | lld:pubmed |
| pubmed-article:9864403 | pubmed:abstractText | We hypothesize that interleukin 1alpha (IL-1alpha) and interleukin 1beta (IL-1beta) are present and tumor cell associated in human breast cancer (HBC) specimens. To test our hypothesis: a) immunologic analysis was performed on HBC histologic sections for IL-1alpha (n=49) and IL-1beta (n=42) distribution; and b) homogenates of HBC tumors were analyzed for levels of IL-1alpha (n=82), IL-1beta (n=101) and interleukin 8 (IL-8) (n=103) expression. Immunohistochemical analysis demonstrated the presence of IL-1alpha and IL-1beta in tumor cells in patients with invasive cancer and ductal carcinoma in situ. Quantitative analysis confirmed the presence and positive correlation of IL-1alpha and IL-1beta to IL-8, a known angiogenic factor, in cancer specimens. These studies demonstrate that tumor-associated IL-1alpha+, IL-1beta are present in the tumor microenvironment and may play a pivotal role in regulating breast tumor growth and metastasis. | lld:pubmed |
| pubmed-article:9864403 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9864403 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9864403 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9864403 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9864403 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9864403 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9864403 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9864403 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9864403 | pubmed:issn | 1021-335X | lld:pubmed |
| pubmed-article:9864403 | pubmed:author | pubmed-author:MillerL JLJ | lld:pubmed |
| pubmed-article:9864403 | pubmed:author | pubmed-author:KreutzerD LDL | lld:pubmed |
| pubmed-article:9864403 | pubmed:author | pubmed-author:WangYY | lld:pubmed |
| pubmed-article:9864403 | pubmed:author | pubmed-author:BarrowsGG | lld:pubmed |
| pubmed-article:9864403 | pubmed:author | pubmed-author:LindquistR... | lld:pubmed |
| pubmed-article:9864403 | pubmed:author | pubmed-author:RennaMM | lld:pubmed |
| pubmed-article:9864403 | pubmed:author | pubmed-author:AndersonK HKH | lld:pubmed |
| pubmed-article:9864403 | pubmed:author | pubmed-author:KurtzmanS HSH | lld:pubmed |
| pubmed-article:9864403 | pubmed:author | pubmed-author:StankusMM | lld:pubmed |
| pubmed-article:9864403 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9864403 | pubmed:volume | 6 | lld:pubmed |
| pubmed-article:9864403 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9864403 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9864403 | pubmed:pagination | 65-70 | lld:pubmed |
| pubmed-article:9864403 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:9864403 | pubmed:meshHeading | pubmed-meshheading:9864403-... | lld:pubmed |
| pubmed-article:9864403 | pubmed:meshHeading | pubmed-meshheading:9864403-... | lld:pubmed |
| pubmed-article:9864403 | pubmed:meshHeading | pubmed-meshheading:9864403-... | lld:pubmed |
| pubmed-article:9864403 | pubmed:meshHeading | pubmed-meshheading:9864403-... | lld:pubmed |
| pubmed-article:9864403 | pubmed:meshHeading | pubmed-meshheading:9864403-... | lld:pubmed |
| pubmed-article:9864403 | pubmed:meshHeading | pubmed-meshheading:9864403-... | lld:pubmed |
| pubmed-article:9864403 | pubmed:meshHeading | pubmed-meshheading:9864403-... | lld:pubmed |
| pubmed-article:9864403 | pubmed:meshHeading | pubmed-meshheading:9864403-... | lld:pubmed |
| pubmed-article:9864403 | pubmed:meshHeading | pubmed-meshheading:9864403-... | lld:pubmed |
| pubmed-article:9864403 | pubmed:meshHeading | pubmed-meshheading:9864403-... | lld:pubmed |
| pubmed-article:9864403 | pubmed:meshHeading | pubmed-meshheading:9864403-... | lld:pubmed |
| pubmed-article:9864403 | pubmed:meshHeading | pubmed-meshheading:9864403-... | lld:pubmed |
| pubmed-article:9864403 | pubmed:meshHeading | pubmed-meshheading:9864403-... | lld:pubmed |
| pubmed-article:9864403 | pubmed:articleTitle | Cytokines in human breast cancer: IL-1alpha and IL-1beta expression. | lld:pubmed |
| pubmed-article:9864403 | pubmed:affiliation | Department of Surgery, University of Connecticut Health Center, Farmington, CT 06030-3105, USA. | lld:pubmed |
| pubmed-article:9864403 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9864403 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9864403 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9864403 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9864403 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9864403 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9864403 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9864403 | lld:pubmed |
