rdf:type |
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lifeskim:mentions |
|
pubmed:issue |
3
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pubmed:dateCreated |
1998-12-21
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pubmed:databankReference |
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pubmed:abstractText |
Fractalkine is the only as yet known member of a novel class of chemokines. Besides its novel Cys-X-X-X-Cys motif, fractalkine exhibits features which have not been described for any other member of the chemokine family, including its unusual size (397 amino acids human, 395 mouse) and the possession of a transmembrane anchor, from which a soluble form may be released by extracellular cleavage. This report demonstrates the abundant mRNA and fractalkine protein expression in neuronal cells. The neuronal expression of fractalkine mRNA is unaffected by experimentally induced inflammation of central nervous tissue.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/CX3CL1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CX3CL1,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokines, CX3C,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokines, CXC,
http://linkedlifedata.com/resource/pubmed/chemical/Cx3cl1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Cx3cl1 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0014-5793
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pubmed:author |
pubmed-author:DairaghiD JDJ,
pubmed-author:IglesiasAA,
pubmed-author:LiningtonCC,
pubmed-author:LynchN JNJ,
pubmed-author:SchäferM KMK,
pubmed-author:SchallT JTJ,
pubmed-author:SchubartAA,
pubmed-author:SchwaebleW JWJ,
pubmed-author:StoverC MCM,
pubmed-author:TrinderP KPK,
pubmed-author:WeigtUU
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pubmed:issnType |
Print
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pubmed:day |
20
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pubmed:volume |
439
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
203-7
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:9845323-Animals,
pubmed-meshheading:9845323-Cells, Cultured,
pubmed-meshheading:9845323-Chemokine CX3CL1,
pubmed-meshheading:9845323-Chemokines, CX3C,
pubmed-meshheading:9845323-Chemokines, CXC,
pubmed-meshheading:9845323-Encephalomyelitis, Autoimmune, Experimental,
pubmed-meshheading:9845323-Female,
pubmed-meshheading:9845323-Humans,
pubmed-meshheading:9845323-Immunohistochemistry,
pubmed-meshheading:9845323-Membrane Proteins,
pubmed-meshheading:9845323-Mice,
pubmed-meshheading:9845323-Neurons,
pubmed-meshheading:9845323-RNA, Messenger,
pubmed-meshheading:9845323-Rats
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pubmed:year |
1998
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pubmed:articleTitle |
Neuronal expression of fractalkine in the presence and absence of inflammation.
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pubmed:affiliation |
Department of Microbiology and Immunology, University of Leicester, UK. ws5@le.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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