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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1999-1-7
|
| pubmed:abstractText |
During an 18-month period in a burn center (January 1995 through June 1996), 109 single-patient MRSA isolates were identified and 102 isolates (94%) were available for DNA fingerprinting. Ninety-nine isolates (97%) carried the mecA polymorph I and Tn554 type E. Pulsed-field electrophoresis (PFGE) identified 8 patterns, of which 60 isolates were of pattern F2. The I:E:F clonal type and a stable drug multidrug resistant phenotype (sensitivity only to trimethoprim/sulfamethoxazole and vancomycin) indicated that these isolates were closely related to the Iberian clone of MRSA, which is widely spread in Europe. The initial source of I:E:F isolates was sputum 49%, blood 23%, wound 16%, urine 7%, and intravascular catheter tip 5%. Fifty-four percent of patients had smoke inhalation injury, and 51/53 required intubation or tracheostomy. Forty-three isolates were considered invasive (positive blood culture). The overall mortality was 30%. Despite infection control measures, the I:E:F clone continued to be recovered from patients during the 18 months of study. This outbreak is the first known report of the Iberian MRSA clone in the United States.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
1076-6294
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
4
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
175-83
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9818969-Adolescent,
pubmed-meshheading:9818969-Adult,
pubmed-meshheading:9818969-Aged,
pubmed-meshheading:9818969-Aged, 80 and over,
pubmed-meshheading:9818969-Burn Units,
pubmed-meshheading:9818969-Child,
pubmed-meshheading:9818969-Child, Preschool,
pubmed-meshheading:9818969-DNA Fingerprinting,
pubmed-meshheading:9818969-Disease Outbreaks,
pubmed-meshheading:9818969-Female,
pubmed-meshheading:9818969-Hospitals, Teaching,
pubmed-meshheading:9818969-Humans,
pubmed-meshheading:9818969-Infant,
pubmed-meshheading:9818969-Infection Control,
pubmed-meshheading:9818969-Male,
pubmed-meshheading:9818969-Methicillin Resistance,
pubmed-meshheading:9818969-Middle Aged,
pubmed-meshheading:9818969-New York City,
pubmed-meshheading:9818969-Staphylococcal Infections,
pubmed-meshheading:9818969-Staphylococcus aureus
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
Outbreak in a New York City teaching hospital burn center caused by the Iberian epidemic clone of MRSA.
|
| pubmed:affiliation |
The New York Hospital-Cornell Medical Center, NY 10021, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|