Linked Life Data

9817742

Source:http://linkedlifedata.com/resource/pubmed/id/9817742

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5 Pt 3
pubmed:dateCreated
1998-12-21
pubmed:abstractText
The contractile state of maximally activated bovine airway smooth muscle is altered during imposed tidal stretches that simulate the action of breathing. When the amplitude of imposed tidal stretch is very small (0.25% of muscle optimal length), the steady-state value of the muscle force, F, approximates the isometric force, the muscle stiffness, E, is large, and the muscle hysteresivity, eta, is small. When the amplitude is increased beyond 1%, however, F and E promptly decrease and eta promptly increases. The provocative stretch amplitude required to cause active force or muscle stiffness to fall by half, or hysteresivity to double, is slightly greater than 2%. By contrast, the stretch amplitude expected during quiet breathing at rest is 4%. Therefore, the isometric force generating capacity of airway smooth muscle may not be applicable to the force generated in normal physiologic circumstances, even during maximal bronchial provocation.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1073-449X
pubmed:author
pubmed:issnType
Print
pubmed:volume
158
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S176-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Dynamically determined contractile states of airway smooth muscle.
pubmed:affiliation
Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA.
pubmed:publicationType
Journal Article, In Vitro, Research Support, U.S. Gov't, P.H.S., Review