Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
|
| pubmed:dateCreated |
1998-11-20
|
| pubmed:abstractText |
Graft-versus-host disease (GVHD) occurring after HLA-identical sibling bone marrow transplantation (BMT) is considered to be mainly caused by minor histocompatibility antigen (mHag) disparities between the recipient and donor. In our laboratory, a human skin explant model has been successfully used to predict acute GVHD in HLA-identical sibling BMT. More recently, the frequency analysis of host-reactive helper and cytotoxic T lymphocyte precursors (HTLp and CTLp, respectively) has been shown to have potential application for predicting GVHD. In the present study, HTLp and CTLp frequency analysis and the skin explant model were directly compared for their ability to predict acute GVHD in HLA-identical sibling BMT.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
0041-1337
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
15
|
| pubmed:volume |
66
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
857-63
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9798694-Acute Disease,
pubmed-meshheading:9798694-Adolescent,
pubmed-meshheading:9798694-Adult,
pubmed-meshheading:9798694-Bone Marrow Transplantation,
pubmed-meshheading:9798694-Female,
pubmed-meshheading:9798694-Forecasting,
pubmed-meshheading:9798694-Graft vs Host Disease,
pubmed-meshheading:9798694-HLA Antigens,
pubmed-meshheading:9798694-Histocompatibility,
pubmed-meshheading:9798694-Humans,
pubmed-meshheading:9798694-Incidence,
pubmed-meshheading:9798694-Male,
pubmed-meshheading:9798694-Middle Aged,
pubmed-meshheading:9798694-Minor Histocompatibility Antigens,
pubmed-meshheading:9798694-Skin,
pubmed-meshheading:9798694-Stem Cells,
pubmed-meshheading:9798694-T-Lymphocytes, Cytotoxic,
pubmed-meshheading:9798694-T-Lymphocytes, Helper-Inducer
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
Predicting graft-versus-host disease in HLA-identical bone marrow transplant: a comparison of T-cell frequency analysis and a human skin explant model.
|
| pubmed:affiliation |
Department of Haematology, School of Clinical and Laboratory Sciences, University of Newcastle, Newcastle-upon-Tyne, United Kingdom.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|